The Fondazione Salvatore Romano is a small museum located right next to the Oltrarno church of Santo Spirito. The museum is located in the ancient Refectory of the convent, erected beside the church of Santo Spirito by the Order of Hermits of St. Augustine. Built in the Gothic style in the 14th century, it is the only part of the magnificent monumental complex of Santo Spirito that still preserves its original structure. Its ancient function is remembered by the imposing 14th century fresco by Andrea Orcagna and his workshop that decorates the entire eastern wall, at the bottom showing the fragments of the Last Supper and at the top, a superb Crucifixion. The fresco is not only one of the best works of Orcagna, but also one of the largest wall paintings of the 14th century to be conserved today. 
The museum displays the works donated to the City of Florence in 1946 by Salvatore Romano, a collector and antiquarian from Campania, who amassed a prestigious collection of sculptures, fragments of architectural decorations, detached frescoes and furniture of various origin and age, from ancient Roman to the 17th century. The display of the works has remained that foreseen by Salvatore Romano himself as per the deed of donation.

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